SGC Research

Dr Metcalf describes how the work of the Salivary Gland Cancer research team will help patients in this short video

There are a number of research projects being undertaken in Manchester, UK, at The Christie NHS Foundation Trust hospital and the University of Manchester. You can learn about some of them below:

Understanding the immune landscape in Adenoid Cystic Carcinoma. 

In immunotherapy the body's own immune system is used to fight cancer by helping it recognise and attack cancer cells.  Dave Morgan, a post-doc researcher working at the Lydia Becker Institute of Immunology and Inflammation at Manchester University, tells us more about his research into ACC here.

The utility of TP53 and PIK3CA mutations as prognostic biomarkers in Salivary Adenoid Cystic Carcinoma

A ground-breaking collaborative UK study led by Dr Metcalf has identified a new sub-type of ACC based on presence of TP53 mutations & associated with more aggressive disease. More research to translate to clinical practice needed.  You can read the full paper here.

The effect of tumour mutational burden in salivary gland cancer

Dr Karan Patel presented at our February 2023 gathering and you can watch the video here.

Rivoceranib - a promising new oral treatment for adenoid cystic carcinoma.

Dr Steve Churchill presented at our February 2023 on the promising new treatment of Rivoceranib. You can watch the video here.