Salivary Gland Cancer UK
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    • The Story so Far - Our 5 year impact Report (2024)
    • Our 8 Aims
    • SGC Research
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  • Treatment Options
    • Diagnosis
    • Surgery
    • Radiotherapy
    • Drug Therapies
      • Drug Therapies - Immunotherapy
    • Clinical Trials
    • Radiofrequency ablation (RFA)
    • Gene profiling or tumour profiling or genomic testing
    • Patient follow up after treatment for SGC
  • Our Stories
    • Alex's story
    • Alison's story
    • Alison C's story
    • Allison D's story
    • Barry's story
    • Christine's story
    • Dawn's story
    • Heather's story
    • Ian's story
    • Jade's story
    • Jamie's story
    • Jev's story
    • Jim's story
    • Kamla's story
    • Karen's story
    • Matilda's story
    • Ruth's story
    • Sarah's story
    • Shane's story
    • Wendy's story
  • Patient and Carer Support
    • Anxiety Management Techniques
    • Exercise for the head, neck and shoulder area
    • Returning to Work
    • Tips on communicating with an electrolarynx
    • How can I best support my mother?
    • Kemi shares her advice for supporting a loved one with cancer
    • Radiotherapy Treatment and Late Effects
      • The Late Effects of Radiotherapy Treatment with Emma Hallam, Consultant Therapeutic Radiographer
      • What is Radiation Induced Fibrosis? And How To Reduce Its Effects
      • Tips for Salivary Gland Cancer Patients Living with Radiotherapy Late Effects
      • Top tips for radiotherapy treatment from our network member Dawn
    • Dawn's tips for someone close to someone with Salivary Gland Cancer
    • Pain
    • Quality of Life (QoL) in Adenoid Cystic Carcinoma (ACC) Patients with Dr Joe Haigh
    • Mindfulness Practice with Emma Hallam, Consultant Therapeutic Radiographer
  • Support SGC UK (and get involved)
    • Join Our Network (and get our newsletter)
    • Donate tissue to the Biobank
    • Our 2025 Events (gatherings and webinars)
    • Donate and help our work
    • Patient – Researcher Trial Discussions
    • Podcasts and Videos
    • Volunteering with SGC UK at a conference or event
    • Salivary Gland Cancer Day - 4th October
    • SGC UK Shareable Resources
    • Leaflets and Flyers
  • Salivary Gland Cancers
    • A guide to different types of Salivary Gland Cancers
    • Acinic Cell Carcinoma (AcCC)
    • Adenocarcinoma
    • Adenocarcinoma, NOS
    • Adenoid Cystic Carcinoma (ACC)
    • Basal Cell Adenocarcinoma (BCAC)
    • Clear Cell Carcinoma (CCC)
    • Mucoepidermoid Carcinoma (MEC) & Warthin-like MEC
    • Salivary Duct Carcinoma (SDC)
    • Secretory Carcinoma (SC)
    • Polymorphus adenocarcinoma (PAC)
    • Carcinosarcoma
    • Myoepithelial carcinoma (MC)
  • Body sites affected by SGC
    • Major Salivary Glands - Parotid, Sublingual and Submandibular
    • Secretory Glands - The Lacrimal Gland
    • Secretory Glands - Bartholin's Gland
    • Secretory Glands - The Lining of the Trachea
    • Skin
    • Nerves in the Head and Neck - Trigeminal Nerve
    • Nerves in the Head and Neck - Optic Nerve
    • Bone Structures in the Face
    • The Spine
  • Fundraising for SGC UK
    • Run
    • Walk
    • Swim
    • Some fundraising ideas
    • Paying in the funds you've raised
    • Fundraising at work
    • Leaving a gift in your will
  • Salivary Gland Cancer Science - Research Updates
    • Tracheal Adenoid Cystic Carcinoma: why studying it matters - and how biobanks help
    • Salivary gland cancer: new classifications and diagnostic challenges
    • New study examining disruption of oncogenic pathways in mucoepidermoid carcinoma (MEC)
    • New study reveals late recurrence and low survival rate of adenoid cystic carcinoma of the breast
    • New study using real-world UK data supports the use of HER2-directed therapies for HER2-positive salivary gland cancers
  • UK Salivary Gland Cancer Research Working Group (UKSGCRWG)
    • Research Working Group Members
    • RQ 1. Address the utility of Guidelines for Salivary Gland Cancers (SGC)
    • RQ 2. Assess the variation in histopathology reporting for Salivary Gland Cancers (SGC)
    • RQ 3. Standardise the decision-making processes for patients who have technically operable, Salivary Gland Cancer (SGC), where the surgery carries high morbidity
    • RQ 4. Improve the diagnostic pathway for Salivary Gland Cancer (SGC) patients
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Working for those with rare salivary gland cancers.

Acinic Cell Carcinoma (AcCC)
Adenocarcinoma
Adenocarcinoma, NOS
Adenoid Cystic Carcinoma (ACC)
Basal Cell Adenocarcinoma (BCAC)
Clear Cell Carcinoma (CCC)
Salivary Duct Carcinoma (SDC)
Secretory Carcinoma (SC)
Mucoepidermoid Carcinoma (MEC)

Acinic Cell Carcinoma (AcCC)

Acinic cell carcinomas account for 1-6% of salivary gland tumours.

Basal Cell Adenocarcinoma (BCAC)

Basal Cell Adenocarcinoma (BCAC) accounts for 1-3% of salivary gland cancers

Carcinosarcoma

Carcinosarcoma accounts for less than 1% of all salivary gland tumours

Polymorphus adenocarcinoma (PAC)

Polymorphous adenocarcinoma (PAC) accounts for around 12% of malignant salivary gland tumours

Myoepithelial carcinoma (MC)

Myoepithelial carcinoma makes up less than 2% of all salivary gland tumours

Salivary Gland Cancer Day - 4th October

26 May 2025

Raising Awareness for a Rare Disease. Welcome to the WORLD'S FIRST Salivary Gland Cancer Day, being held annually on the 4th of October.

UK Salivary Gland Cancer Research Working Group (UKSGCWG)

26 May 2025

This working group is to identify the gaps in Salivary Gland Cancer Research, develop strategic priorities for this area of research and deliver them.

Adenoid Cystic Carcinoma (ACC)

Adenoid Cystic Carcinoma (ACC)

The Story so Far - Our 5 year impact Report (2024)

28 Jan 2025

Our impact report showcases all the progress that's been made in just five years (2019-2024)

SGC Travel Grants

Apply for funding to travel to a conference or workshop. We welcome all applications that are aligned with our strategy.

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Salivary Gland Cancers
Our Stories
Patient and Carer Support
Support SGC UK (and get involved)
about 21 hours ago After undergoing radiotherapy for adenoid cystic carcinoma, artist Alex Orange Drink has released a powerful new single, Everything Is Broken — a raw and honest reflection on navigating treatment, uncertainty and the emotional weight of cancer. Through music, Alex turns vulnerability into strength, sharing a message that will resonate with many in our community. “I didn’t know if I’d ever sing again... This was the first thing I wrote when I tried.” Listen to the track and read the story behind it: #SalivaryGlandCancer #AdenoidCysticCarcinoma #SGCUK #CancerAwareness @SGCancerUK
about 2 days ago On June 1st, we took time to think of everyone who has lived through a cancer diagnosis, including so many in our salivary gland cancer community. This day is about recognising what it takes to move forward after treatment. The strength it takes to heal, adjust and carry on. Every journey is different and every step matters. If you've finished treatment, are still being monitored, or just figuring things out as you go, we see you. We're with you. And if you feel like sharing your story, we’d love to hear it, either in the comments or by dropping us a message. #NationalCancerSurvivorsDay #SGCUK #SalivaryGlandCancer #CancerAwareness #LifeAfterCancer #SupportCommunity #StrongerTogether @SGCancerUK
about 9 days ago Facing salivary gland cancer can feel overwhelming, but you do not have to go through it alone.💙 Whether you are newly diagnosed, going through treatment, or in remission, our community is here to support you every step of the way. We understand the emotional and physical challenges, and we are here to help you stay strong and resilient. Reach out, connect with others who truly understand, and remember that we are all stronger together. #SupportMatters #StrongerTogether #SalivaryGlandCancer @SGCancerUK
At the ABPI/PMCPA code partnership event we were delighted to share our collaborative work with Roche, co-producing genomics leaflets for patients.

The leaflets we created are free to download from our website, specifically designed to be clear and understandable for all and, explain why genomic profiling is important and how it can help patients https://lnkd.in/ebh9-xMU. Later this year we will be updating the leaflets so don't hesitate to get in touch if you'd like to work with us on this.

The meeting showcased three very different, but truly great, Industry-Charity Partnerships. We were delighted to be joined by Crohn's & Colitis UK who partnered with J&J Innovative Medicine Europe, Middle East & Africa (EMEA) and, Black Women Rising UK who partnered with Gilead Sciences.

Our thanks go to the The Association of the British Pharmaceutical Industry (ABPI) and PMCPA for hosting the event, Karen Wood for co-presenting with Emma Kinloch and, all those who support, facilitate and do the hard work to ensure the success of these hugely important collaborations.

👏

Tariro Kabba Mearns & Pike Ltd Leanne Pero MBE Hannah Hart Kate Downey The Association of the British Pharmaceutical Industry (ABPI) Amit Aggarwal Brian Duggan Victoria Bates

#ABPI #PMCPA #salivaryglandcancer #co-production #collaboration
#ppi #genomicprofiling #genomics #blackwomenrising #crohns #rarecancerresearch
@sgcanceruk
A constructive and informative session hosted by Department of Health and Social Care to share our knowledge and expertise and, shape the National Cancer Plan.

Our thanks to Cancer52, all our rare cancer charity colleagues, Ashley Dalton MP and the Department of Health and Social Care for their engagement, and commitment to collaboration and informed decision-making.

We look forward to future discussions and as always, stand ready to help.

#NationalCancerPlan #RareCancer #Salivaryglandcancer #collaboration #cancercharity
@sgcanceruk
about 14 days ago Exciting progress in salivary gland cancer research 💙 Researchers at the University of Chicago Medicine have used artificial intelligence to identify a promising new therapeutic target for adenoid cystic carcinoma (ACC) – a rare and difficult-to-treat form of salivary gland cancer. By analysing tumour samples with advanced AI tools, scientists discovered that targeting an enzyme called PRMT5 could help slow cancer growth. In early lab studies, a drug called PRT543 showed encouraging results in reducing tumour size. While this is not yet a cure, it marks an important step towards more effective treatments for ACC. Read more about the research here: #SalivaryGlandCancer #ACCUK #CancerResearch #AIinMedicine #HopeThroughScience #SGCUK @SGCancerUK
about 14 days ago Exciting progress in salivary gland cancer research 💙 Researchers at the University of Chicago Medicine have used artificial intelligence to identify a promising new therapeutic target for adenoid cystic carcinoma (ACC) – a rare and difficult-to-treat form of salivary gland cancer. By analysing tumour samples with advanced AI tools, scientists discovered that targeting an enzyme called PRMT5 could help slow cancer growth. In early lab studies, a drug called PRT543 showed encouraging results in reducing tumour size. While this is not yet a cure, it marks an important step towards more effective treatments for ACC. Read more about the research here: #SalivaryGlandCancer #ACCUK #CancerResearch #AIinMedicine #HopeThroughScience #SGCUK @SGCancerUK
Exciting progress in salivary gland cancer research 💙

Researchers at the University of Chicago Medicine have used artificial intelligence to identify a promising new therapeutic target for adenoid cystic carcinoma (ACC) – a rare and difficult-to-treat form of salivary gland cancer.

By analysing tumour samples with advanced AI tools, scientists discovered that targeting an enzyme called PRMT5 could help slow cancer growth. In early lab studies, a drug called PRT543 showed encouraging results in reducing tumour size.

While this is not yet a cure, it marks an important step towards more effective treatments for ACC.

Read more about the research here:
https://lnkd.in/eAkcncGM

#SalivaryGlandCancer #ACCUK #CancerResearch #AIinMedicine #HopeThroughScience #SGCUK
@sgcanceruk
about 19 days ago We had a truly special day in Sheffield last weekend, bringing together members of our community for connection, support and shared understanding. These gatherings offer a space where people affected by salivary gland cancer can meet others who understand. Whether newly diagnosed, in treatment, post-treatment or supporting someone close, everyone is welcome. Thank you to everyone who came along. Your kindness, openness and strength made it a day we will not forget. To find out about our future gatherings, visit: #SGCUK #SalivaryGlandCancer #CancerSupportCommunity #SGCEvents #CancerAwareness #TogetherInSupport @SGCancerUK
about 20 days ago Some days feel heavier than others. But even in the toughest moments, looking for the light can help us move forward with hope and strength. This quote is a reminder that your mindset matters and that brighter days are always possible. 💙 Save this post for when you need a little encouragement and share it with someone who might need it too. #SalivaryGlandCancer #SGCUK @SGCancerUK
about 21 days ago Last week, our UK Salivary Gland Cancer Research Working Group came together in Sheffield for a focused and productive session. This multidisciplinary group of researchers, clinicians and advocates are working to improve the understanding, diagnosis and treatment of salivary gland cancers across the UK. Together, we adressed key priorities including: 🔹 Reviewing and refining clinical guidelines 🔹 Standardising pathology reporting 🔹 Improving diagnostic pathways 🔹 Supporting more effective decision-making in complex cases Every discussion brings us one step closer to stronger, evidence-based care for people affected by salivary gland cancer. Want to know more or get involved? Visit: #SalivaryGlandCancer #SGCUK #CancerResearch #UKSGCRWG #HeadAndNeckCancer #PatientCare #ResearchInAction @SGCancerUK
about 24 days ago 💙 International Nurses Day 💙 Today we’re celebrating the dedicated nurses and nurse advocates who are part of our UK Salivary Gland Cancer Research Working Group. From the clinic to the lab, and into the heart of patient advocacy, they bring a wealth of experience, compassion and leadership to the work we do. 💬 Samantha Rokoszynski, a registered nurse and patient living with adenoid cystic carcinoma, brings a powerful dual perspective. With 25 years in the NHS and her lived experience, she is a strong advocate for collaboration between patients, professionals and researchers. 💙 Andrea Nelson, Senior Macmillan Clinical Nurse Specialist in Head and Neck Cancer at London Northwest University Trust, has dedicated more than 20 years to supporting patients through some of the most life-changing treatments. She leads with empathy, expertise and a deep commitment to improving care pathways and national policy. We’re proud to work alongside such inspiring professionals who continue to shape the future of care for those affected by salivary gland cancer. Thank you for everything you do today and every day. #InternationalNursesDay #SGCUK #SalivaryGlandCancer #HeadAndNeckCancer #CancerNursing #NurseLeadership #NursesDay2025 #TeamSGCUK #CancerCare #NursingExcellence @SGCancerUK
💙 International Nurses Day 💙

Today we’re celebrating the dedicated nurses and nurse advocates who are part of our UK Salivary Gland Cancer Research Working Group.

From the clinic to the lab, and into the heart of patient advocacy, they bring a wealth of experience, compassion and leadership to the work we do.

💬 Sammy Rokoszynski, a registered nurse and patient living with adenoid cystic carcinoma, brings a powerful dual perspective. With 25 years in the NHS and her lived experience, she is a strong advocate for collaboration between patients, professionals and researchers.

💙 Andrea Nelson, Senior Macmillan Cancer Support Clinical Nurse Specialist in Head and Neck Cancer at London Northwest University Trust, has dedicated more than 20 years to supporting patients through some of the most life-changing treatments. She leads with empathy, expertise and a deep commitment to improving care pathways and national policy.

We’re proud to work alongside such inspiring professionals who continue to shape the future of care for those affected by salivary gland cancer.

Thank you for everything you do today and every day.

#InternationalNursesDay #SGCUK #SalivaryGlandCancer #HeadAndNeckCancer #CancerNursing #NurseLeadership #NursesDay2025 #TeamSGCUK #CancerCare #NursingExcellence
@sgcanceruk
about 28 days ago There are so many ways to support our work – and every single one helps us move closer to better research, better awareness, and better outcomes for those living with salivary gland cancer. Here are 5 ways you can make an impact 💙 Which one will you choose? Visit our website for all the details. #SalivaryGlandCancer #SGCUK #FundraisingForHope #SupportSGCUK #CancerAwareness #MakeADifference @SGCancerUK
about a month ago We’ve set an ambitious fundraising goal of £150,000, and we need your help to achieve it! Do you love sport and adventure? Here are some exciting fundraising ideas perfect for any sporty, adrenaline enthusiast looking to make a real difference! Your efforts will help fund vital research and provide support for those affected by salivary gland cancer. Whether you’re organising a race, taking on a physical challenge, or pushing your limits in another way, every step you take brings us closer to the future we all want to see. Let’s make this happen together! 💙 #SGCDay #SGCUKDay #SalivaryGlandCancerDay #SalivaryGlandCancerUKDay #SGCDayFundraiser #SalivaryGlandCancerDayFundraiser #SalivaryGlandCancerFundraiser #SGCUKFundraiser @SGCancerUK
about a month ago This month, we’re coming together for a special event where you can connect with others who truly understand. Whether you're living with salivary gland cancer or supporting someone who is, this is a chance to share your journey and find support in a caring community. Join us to listen, learn, and uplift one another in a welcoming space. 📅 Date: Saturday, May 10th, 2025 📍 Location: Sheffield For more details, visit our website. We can’t wait to see you there! 💙 #SGC #SGCUK #SalivaryGlandCancerAwareness #CancerSupportCommunity #CancerAwarenessCampaign @SGCancerUK
about a month ago 🗓️ Our next UK Salivary Gland Cancer Research Working Group meeting takes place next month on Friday 9 May 2025 in Sheffield. This collaborative group brings together leading researchers, clinicians and advocates from across the UK, all focused on improving the understanding, diagnosis and treatment of salivary gland cancers. Together, we're working to: 🔹 Review and refine clinical guidelines 🔹 Standardise pathology reporting 🔹 Improve diagnostic pathways 🔹 Support better decision-making in complex cases It’s all about building stronger, evidence-based care for everyone affected by salivary gland cancer. Want to know more or get involved? Visit our website for details: #SalivaryGlandCancer #SGCUK #UKSGCRWG #CancerResearch @SGCancerUK
about a month ago 🎉 Help Us Win £5,000! 🎉 The Health & Wellbeing Special Draw by the Benefact Group is OPENING TODAY — and we need your nomination! 💙 10 charities will each receive £5,000, and your nomination could help Salivary Gland Cancer UK secure vital funding for support services, awareness campaigns and research. It only takes a minute to nominate us — and it could make a huge difference to people living with salivary gland cancer. 📣 Please share and spread the word! Thank you for your support 💙 Nominate us here: #SGCUK #SalivaryGlandCancer #HealthAndWellbeing @SGCancerUK
Help Us Win £5,000!

The Health & Wellbeing Special Draw by the Benefact Group is OPENING TODAY — and we need your nomination!

10 charities will each receive £5,000, and your nomination could help Salivary Gland Cancer UK secure vital funding for support services, awareness campaigns and research.

It only takes a minute to nominate us — and it could make a huge difference to people living with salivary gland cancer.

Please share and spread the word!

Thank you for your support!

#SGCUK #SalivaryGlandCancer #HealthAndWellbeing

https://lnkd.in/e9d-rANa
@sgcanceruk
about a month ago A diagnosis of salivary gland cancer can feel isolating, but no one should face it alone. Whether you’re a patient, a loved one, or a supporter, coming together makes a world of difference. Through shared experiences, encouragement, and understanding, we create a network of strength and hope. Your voice, your story, and your support help build a compassionate space where everyone feels heard. Join us in raising awareness, offering kindness, and making sure no one is left behind. Together, we are stronger. 💙 #SalivaryGlandCancer #CancerAwareness #CancerSupport #CancerSupportNetwork #SalivaryGlandCancerResearch @SGCancerUK
about a month ago Connecting with others who understand can make all the difference. Whether you’re living with salivary gland cancer, supporting a loved one, or simply want to be part of a caring community, we’d love to see you there. Come along for a chance to share experiences, find support, and meet others in a warm and welcoming space. Let’s come together to listen, learn, and uplift one another. 📅 Date: Saturday, May 10th 2025 📍 Location: Sheffield You can find more details on our website. Everyone is welcome—let us know if you’ll be joining us! 💙 #SGC #SGCUK #SalivaryGlandCancerAwareness #CancerSupportCommunity #CancerAwarenessCampaign @SGCancerUK
about 2 months ago The trigeminal nerve is one of twelve nerves that leave the brain via holes in the skull. These nerves are known as cranial nerves and are numbered. The trigeminal nerve is the 5th cranial nerve. Like all cranial nerves, the trigeminal nerve is a pair with one on each side of the head. It leaves the skull through a hole in front of the ear and splits into three branches that lead to different parts of the face, as shown in the diagram. These are the ophthalmic nerve, the maxillary nerve, and the mandibular nerve. The trigeminal nerve is mainly a sensory nerve- this means it carries information about sensations to the brain. It also has some motor functions — this means it carries signals from the brain that tell muscles to move. The ophthalmic nerve is a sensory branch and carries sensations from the top part of the face including the area around the eye. It also carries sensations from the outside of the eyeball itself. However, it is not responsible for eyesight and damage to the nerve does not result in loss of vision. The maxillary nerve is also a sensory branch and carries sensations from the middle part of the face around the cheeks and nose. It is not responsible for the sense of smell and damage to the nerve does not result in loss of smell. The mandibular nerve is both a sensory and motor branch. It carries sensations from the lower part of the face around the jaw and mouth. It also supplies the muscles used for chewing and is needed to chew. The trigeminal nerve passes close to the parotid salivary gland in front of the ear and can be affected by cancers growing in that gland. If these cancers press on the nerve and squish it or grow along the nerve, it can cause damage to the nerve that results in changes to the sensation of the face. At the severe end, this can result in the complete loss of sensation. Damage to the nerve can also affect the ability to chew. #TrigeminalNerve #RareCancerResearch #RareDiseaseResearch #CancerResearch #SalivaryGlandCancerResearch #MedicalResearch #trismus @SGCancerUK
As a consultant radiographer and researcher, Nicola has dedicated her work to improving outcomes for people affected by head and neck cancer. But her connection to this cause is not just professional. It is deeply personal.

Motivated by her own experiences and the stories of patients she has worked with, Nicola took her commitment beyond the clinic and into the world of fundraising, choosing to run 26.2 miles to raise awareness and support for our salivary gland cancer community. Salivary gland cancers as rare head and neck cancers, are often overlooked.

Read more about Nicola’s journey, her groundbreaking work, and what inspired her to take on such a meaningful challenge: https://lnkd.in/eez7a3ws

#TeamSGC #SGCawareness #SalivaryGlandCancer #Radiography #CancerResearch #Inspiration #HealthcareProfessionals #NHS #RareCancerResearch #RareCancerAwareness #RareCancer Leicester Royal Infirmary The Royal College of Radiologists Lucy Gardner

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@sgcanceruk
about 2 months ago As a consultant radiographer and researcher, Nicola has dedicated her work to improving outcomes for people affected by head and neck cancer. But her connection to this cause is not just professional. It is deeply personal. Motivated by her own experiences and the stories of patients she has worked with, Nicola took her commitment beyond the clinic and into the world of fundraising, choosing to run 26.2 miles to raise awareness and support for our salivary gland cancer community. Salivary Gland Cancers as rare head and neck cancers, are often overlooked. Her story is a powerful example of how personal experience can shape professional purpose and lead to real impact, both in research and in raising awareness. Read more about Nicola’s journey, her groundbreaking work, and what inspired her to take on such a meaningful challenge: #TeamSGC #SGCawareness #SalivaryGlandCancer #Radiography #CancerResearch #Inspiration #HealthcareProfessionals #NHS #RareCancerResearch #RareCancerAwareness #RareCancer #headandneckcancerawareness #headandneckcancer Leicester royal infirmary past and present @SGCancerUK
about 2 months ago On Sunday our brilliant runners took on the Brighton Marathon and absolutely smashed it! After months of dedicated training, they were met with glorious sunshine on the big day (thankfully with a few water sprinklers along the way to cool off 🌞💦) We’re so incredibly proud of everyone who ran in support of Salivary Gland Cancer awareness – your dedication means the absolute world! Big shoutout to Nicola, Jenna, Kerry, Lucy, Libby, Hope and all the others who took part. You did us all proud and helped raise vital awareness and support for those affected by salivary gland cancer. Also a massive well done to Zo Zo who took on the London Landmarks Half Marathon this weekend. Another incredible effort for the cause 👏 We are so proud of each and every one of you 💪 #BrightonMarathon #LondonLandmarksHalfMarathon #ZoZo #SGCawareness #SalivaryGlandCancer #TeamSGC #FundraisingHeroes #MarathonLegends @SGCancerUK
💡 Research Update: New hope for mucoepidermoid carcinoma (MEC) treatment

Mucoepidermoid carcinoma is the most common salivary gland cancer, yet treatment options remain limited. Surgery and radiotherapy can impact quality of life, and chemotherapy offers little success.

New research from teams in Brazil and the UK has explored an approach going for a new drug target (the CREB pathway), which drives the growth of cancer.  A brand new drug (known CREB inhibitor called 666.15) was tested on MEC cells with differing genotypes.

A good effect at killing cancer cells was seen which may benefit up to half of MEC patients who express a so-called fusion gene. This new drug reduced cancer cell survival, slowed cell migration, and increased levels of E-cadherin, a protein that inhibits metastasis.  The effect of the inhibitor was found to vary according to whether the cells expressed the fusion gene.

👉 While early-stage, this research underscores the potential for personalized medicine in MEC treatment.

Read more about this crucial work in our new article https://lnkd.in/e-xFHmid

#CancerResearch #SalivaryGlandCancer #MEC #PersonalizedMedicine #TargetedTherapy #CREB #FusionGene

Lynne Bingle Robert Metcalf
@sgcanceruk
about 2 months ago Good luck to our incredible marathon runners who are running in the Brighton Marathon today! 💙🏃‍♂️ A special thanks to Jenna, Kerry, Lucy, Jev, Libby, Hope, Nik, Emma, and everyone else who is taking part. Every step you take, every mile you cover, and every moment of determination helps raise awareness and support for those affected by salivary gland cancer. Your dedication means the world, and we are so proud to have you running for our cause. Enjoy the day, soak up the atmosphere, and know that we’re cheering you on every step of the way! 👏 #SGC #SGCUK #SGCDayFundraiser #SalivaryGlandCancerDayFundraiser #SalivaryGlandCancerFundraiser #SGCUKFundraiser @SGCancerUK
about 2 months ago Today, we celebrate six years of raising awareness, funding research, and supporting those affected by salivary gland cancer. What started as a small idea has grown into a community filled with kindness, resilience, and hope. We couldn’t have done it without you – our supporters, fundraisers, and everyone who has shared their story. Thank you for being part of this journey. Here’s to the next chapter and making an even bigger impact together! 💙 #SGCUK #SalivaryGlandCancerUK #SGCAwareness #SupportSalivaryGlandCancerPatients #Cure4SGC #SalivaryGlandCancerUK #SalivaryGlandCancerUpdates @SGCancerUK
about 2 months ago Loren Stokes, from Shrewsbury, faced a challenging battle with cancer that led to the removal of her larynx, thyroid, salivary glands, and part of her oesophagus. Despite speaking through a voice prosthesis, Loren’s strength and positivity never wavered. Sadly, Loren passed away on 6 March, but her friends Jenna Wakenshaw and Jenny Hughes are honouring her memory by raising funds for the Salivary Gland Cancer Charity and The Christie Hospital. To date, over £3,500 has been raised to support Loren’s family and further our mission to raise awareness of salivary gland cancer. 💙 Read more about Loren’s story here: #SalivaryGlandCancer #SGCCharity #CancerAwareness @SGCancerUK
about 2 months ago Salivary gland cancer is rare, but the need for awareness, research, and support is great. We’re calling on you to help us make an impact for the launch of the WORLD's FIRST Salivary Gland Cancer Day! We have a fundraising goal of £150,000. Whether you’re hosting a bake sale, taking on a challenge, or making a donation, your contribution helps fund vital research and provides support for those affected. Let’s come together to raise awareness and bring hope to those who need it most. Every month we'll share with you some ideas on how you can contribute within your own community. Here are some ideas for the arts and crafts lovers! How will you get involved? 💙 #SGCDay #SGCUKDay #SalivaryGlandCancerDay #SalivaryGlandCancerUKDay #SGCDayFundraiser #SalivaryGlandCancerDayFundraiser #SalivaryGlandCancerFundraiser #SGCUKFundraiser @SGCancerUK

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hello@salivaryglandcancer.uk

Salivary Gland Cancer UK, International House, 36-38 Cornhill, London EC3V 3NG

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Salivary Gland Cancer UK is a registered charity number 1182762.